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Trivia # 43: acetylcholinesterase

17 October, 2009
Toxicological trivia from October 16, 2009: Acetylcholinesterase, also known as AChE, is an enzyme that degrades (through its hydrolytic activity) the neurotransmitter acetylcholine, producing choline and an acetate group. It is mainly found at neuromuscular junctions and cholinergic synapses in the central nervous system, where its activity serves to terminate synaptic transmission.Choline and an acetate group then are:
a) Reabsorbed by the first nerve cell (presynaptic);
b) Tecycled to form more acetylcholine;
c) The answers a and b are correct.
Trivia # 43: acetylcholinesterase
Answer c. Read more in Poisoning by pesticides and nerve impulse transmission (Only available in Spanish)


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