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 Recomendamos: Medication errors seen in half of 277 operations; 80 percent of the mistakes were preventable, Study

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An anesthesiologist (Foto: nlm.nih.gov)

Medication errors found in 1 out of 2 surgeries. By Sue McGreevey. news.harvard.edu. October 25, 2015. Adverse drug events included in the study of 277 operations at MGH. The first study to measure the incidence of medication errors and adverse drug events during the perioperative period — immediately before, during and right after a surgical procedure — has found that some sort of mistake or adverse event occurred in every second operation and in 5 percent of observed drug administrations. The study of more than 275 operations at Harvard-affiliated Massachusetts General Hospital (MGH), which will appear in Anesthesiology, also found that a third of the errors resulted in adverse drug events or harm to patients. The report is being published online to coincide with a presentation at the Anesthesiology 2015 annual meeting in San Diego, Calif., Oct. 24-28.

MedicationWikiCommons

Credit: Wikipedia

“Prior to our study, the literature on perioperative medication error rates was sparse and consisted largely of self-reported data, which we know under-represents true error rates. Now that we have a better idea of the actual rate and causes of the most common errors, we can focus on developing solutions to address the problems," said Karen C. Nanji of the MGH Department of Anaesthesia, Critical Care, and Pain Medicine, lead author of the report.


“We found that just over one in 20 perioperative medication administrations resulted in a medication error or an adverse drug event,” said Karen C. Nanji of the MGH Department of Anaesthesia, Critical Care, and Pain Medicine, lead author of the report.

“Prior to our study, the literature on perioperative medication error rates was sparse and consisted largely of self-reported data, which we know under-represents true error rates. Now that we have a better idea of the actual rate and causes of the most common errors, we can focus on developing solutions to address the problems.

“Given that Mass. General is a national leader in patient safety and had already implemented approaches to improve safety in the operating room, perioperative medication error rates are probably at least as high at many other hospitals,” said Nanji, who is also an assistant professor of anaesthesia at Harvard Medical School (HMS).

Nanji explained that, while drug orders on inpatient floors go through a process in which they are checked several times by different providers (the ordering physician, pharmacist, and nurses administering the medications), the speed with which the condition of patients in the operating room can change doesn’t allow time for double- and triple-checking during surgery.

Although operating rooms at MGH and other hospitals have installed electronic documentation and bar-coded syringe labeling systems to reduce errors in other patient care, the measures that have reduced the occurrence of errors have all started with a rigorous analysis of the incidence and type of errors that were occurring.

To conduct such an analysis for perioperative settings, four specially trained members of the research team observed 225 anesthesia providers (anesthesiologists, nurse anesthetists, and resident physicians) during 277 randomly selected operations conducted at MGH from November 2013 to June 2014. From the time a provider took responsibility for a patient in the preoperative area until the patient arrived in the recovery room or intensive-care unit, the observers documented every medication administration, including any errors. “Errors” were defined as any kind of mistake in the process of ordering or administering a drug or an adverse drug event, which includes harm or injury to a patient related to a drug, whether or not it was caused by an error.

To catch events not apparent to the observers and to confirm that the events they flagged were actually errors, team members also reviewed chart data from the hospital’s anesthesia information management system for all patients whose care had been observed. The study team met weekly to review the recorded events, determine whether they constituted true medication errors or adverse drug events, and classify them by their severity and whether or not they could have been prevented.

Overall, it was determined that 124 of the 277 observed operations included at least one medication error or adverse drug event. Of the almost 3,675 medication administrations in the observed operations, 193 events, involving 153 medication errors and 91 adverse drug events, were recorded either by direct observation or by chart review. Almost 80 percent of those events were determined to have been preventable. One-third of the observed medication errors led to an adverse drug event, and the remainder had the potential to cause an adverse event. Of the adverse drug events that were recorded, 20 percent were not associated with a medication error.

The most frequently observed errors were mistakes in labeling, incorrect dosage, neglecting to treat a problem indicated by the patient’s vital signs, and documentation errors. Of all the observed adverse drug events and medication errors that could have resulted in patient harm — four of which were intercepted by operating room staff before affecting the patient — 30 percent were considered significant, 69 percent serious, and less than 2 percent life-threatening; none were fatal. The overall medication error rate of around 5 percent was the same among anesthesiologists, nurse anesthetists, and residents. Medication errors and adverse drug events were more common with longer procedures, especially those lasting more than six hours and involving 13 or more medication administrations.

“While the frequency of errors and adverse events is much higher than has previously been reported in perioperative settings, it is actually in line with rates found in inpatient wards and outpatient clinics, where error rates have been systematically measured for many years,” said Nanji.

“We definitely have room for improvement in preventing perioperative medication errors, and now that we understand the types of errors that are being made and their frequencies, we can begin to develop targeted strategies to prevent them. We already have an electronic anesthesia management and documentation system for medications, patient vital signs, and other events occurring in the operating room; and our next step will be to design more comprehensive decision support to further reduce the incidence of errors in the perioperative setting, something that I suspect the MGH will be one of the first centers to have in place.”

“This study is especially valuable because it looked in a detailed way into medication errors in the operating room, where many of the safety strategies used in other settings have not yet been adopted, and used trained observers to document these errors,” added the study’s senior author, David Bates of the Department of Medicine at Brigham and Women’s Hospital and HMS professor of medicine. “The operating room has been a hard environment to evaluate, but we used observers familiar with anesthetic care to do the observation.”

Enviado por jcp el 27 octubre 2015 00:00:00 (515 Lecturas)






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País: Estados Unidos y Canadá

 
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