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 Toxicología al día: FDA announced that the risk of side effects for 'An Aspirin A Day ...' may outweigh the benefits

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Molécula de aspirina (Foto: WP)

FDA: An Aspirin A Day Might Not Prevent Heart Problems, Stroke In People Who Never Had One
By Anthony Rivas. medicaldaily.com. May 5, 2014.“An aspirin a day,” they say, will keep heart attacks at bay. While this is the case for many people around the country, the Food and Drug Administration (FDA) announced on Monday that the risk of side effects may outweigh the benefits, especially in people who haven’t experienced a stroke or heart attack — a practice known as “primary prevention.” “Since the 1990s, clinical data have shown that in people who have experienced a heart attack, stroke, or who have a disease of the blood vessels in the heart, a daily dose of aspirin can help prevent a reoccurrence,” Dr. Robert Temple, deputy director of clinical science at the FDA, said in a press release. With about 20 percent of U.S. adults using aspirin either every day or every other day, according to an estimate from the Agency for Healthcare Research and Quality, millions of people could be at risk for adverse effects.


aspirin
Though many people undergo preventive therapy for heart attacks and stroke by taking an aspirin a day, the FDA says there's not enough evidence to prove it, and that people might end up suffering from the drug's side effects instead. Photo courtesy of Shutterstock


At best, the effects of aspirin on people without heart conditions are inconclusive. The FDA noted that the data does not “support the use of aspirin as a preventive medication by people who have not had a heart attack, stroke, or cardiovascular problems,” and that these people may instead experience side effects such as “dangerous bleeding into the brain or stomach.” In fact, one study found that using too much aspirin, and ibuprofen, may increase the risk of stroke, as companies add sodium to the drugs in order to improve absorption. Another one found that long-term use, as is common with people undergoing preventive treatment, may result in vision loss.

Aspirin works by thinning blood to the point that it’s unable to clot, therefore preventing obstruction in the arteries, and allowing blood to travel to the heart. Patients who are already at risk of heart problems and stroke can obviously benefit from taking aspirin, but those who aren’t may be thinning their blood for no reason. Temple advises anyone looking into daily aspirin therapy to speak with a physician, who can weigh the risks and benefits while also prescribing a specific dose — doses range from 80 milligrams to 325 milligrams.

“The terms that we talk about — even what is the difference between primary and secondary prevention — may be lost on the individual patient,” Dr. Gregg Fonarow, a representative for the American Heart Association, told Reuters. He believes the FDA statement could cause some confusion, and said that speaking to a doctor before making any changes is important, whether taking aspirin already or not.  

“It is critical that patients who are already on aspirin therapy remain so,” spokesman for aspirin maker Bayer Chris Loder said in a statement, according to Reuters. “No one should stop or modify their aspirin regimen without first consulting with a health care provider. For those already on aspirin therapy, suddenly stopping can be dangerous.” 
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Watch video: An aspirin a day may not keep a heart attack at bay.WeathersPaulaVid· May 06, 2014.FDA advisory warns against daily aspirin therapy to prevent heart attack in people with low risk of heart disease. FDA advisory warns against daily aspirin therapy to prevent heart attack in people with low risk of heart disease. FDA advisory warns against daily aspirin therapy to prevent heart attack in people with low risk of heart disease.


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Enviado por jcp el 06 mayo 2014 00:00:00 (810 Lecturas)






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