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Visit also our Spanish page. 

On May 31, 2017, the Toxicology Service of the Children's Sanatorium was finished its activities. We continue this page as Latin American Portal of Toxicology.

November 2017 Newsletter: See

 Diseases caused by pollution were responsible in 2015 for 16 percent of all deaths worldwide

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Todo tipo de contaminación (Photo: SerTox)

Pollution responsible for 16 percent of early deaths globally. sciencedaily.com. October 20, 2017. Summary: Diseases caused by pollution were responsible in 2015 for an estimated 9 million premature deaths -- 16 percent of all deaths worldwide, according to a report.Simon Fraser University health sciences professor Bruce Lanphear is a Commissioner and author of The Lancet Commission on Pollution and Health that has released a report detailing the adverse effects of pollution on global health.

FULL ARTICLE...
Posted by jcp on Lunes, octubre 23 @ 00:00:00 ART (25 reads)

 Skin decontamination immediately after fighting a fire may help reduce exposure to carcinogens

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Bomberos luchando contra el fuego (Photo: WP)

Firefighters Exposed to Carcinogens Through the Skin. By Robert Preidt. medlineplus.gov.  October 18, 2017. Immediate decontamination might help reduce harms of contact with hazardous chemicals, study suggests. Firefighters face many known hazards on the job, but one area that hasn't been well researched is how their skin's exposure to hazardous chemicals might increase their risk of cancer. It has long been known that firefighters have higher rates of several types of cancer than people in the general population.

FULL ARTICLE...
Posted by jcp on Viernes, octubre 20 @ 00:00:00 ART (17 reads)

 Scorpions can fine-tune their venom to suit different predators and prey

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Detalle de la cola inoculadora de veneno del Tityus Trivitatus (Photo: Sertox )

JCU scientists find scorpions target their venom. jcu.edu.au. October 11, 2017. In the first study of its kind, James Cook University scientists have shown scorpions can fine-tune their venom to suit different predators and prey. Dr Jamie Seymour from JCU’s Australian Institute of Tropical Health and Medicine (AITHM) said a typical scorpion predator would be a small mammal, while its prey was usually an insect. He said varieties of scorpion toxin worked better depending on whether they were used to protect themselves from predators or kill prey.

FULL ARTICLE...
Posted by jcp on Miércoles, octubre 11 @ 00:00:00 ART (25 reads)

 NOACs* can be significantly altered through interaction with other drugs

Blood Thinners Can Come With Dangerous Side Effects. medlineplus.gov. October 3, 2017. Newer class of drugs can interact with multiple medications, researchers report. Blood-thinning drugs can save your life by preventing a heart attack or stroke caused by artery-blocking blood clots. But these are powerful drugs, and a pair of new studies detail side effects people need to understand before taking them. The effectiveness of a class of blood thinners called nonvitamin K oral anticoagulants (NOACs) can be significantly altered through interaction with other drugs, the first study reveals.
*NOACs = nonvitamin K oral anticoagulants

FULL ARTICLE...
Posted by jcp on Jueves, octubre 05 @ 00:00:00 ART (25 reads)

 Patients who receive opioids at lower doses are less likely to progress to long term use

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Sobredosis de metadona y otros opioides (Photo: CDC)

ERs Prescribing Opioids at Lower Doses, Shorter Durations. By Mary Elizabeth Dallas. medlineplus.gov. September 26, 2017. Patients who receive these prescriptions are less likely to progress to long-term use, study shows. Emergency room doctors write lower-dose, shorter-term prescriptions for opioids than other doctors do, new research shows. The study, led by scientists at the Mayo Clinic, challenges views that emergency departments are the main source of prescriptions for the powerful painkillers whose use -- and misuse -- has soared in recent years.The research also suggests that patients who get an opioid prescription -- such as for oxycodone (OxyContin) -- during an ER visit are less likely to abuse the drugs over the long term.

FULL ARTICLE...
Posted by jcp on Jueves, septiembre 28 @ 00:00:00 ART (87 reads)

 Dermatology expert offers advice on tick removal and avoiding them in the first place

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Garrapatas (Photo: misionesonline.net)

Don't Let the Tick Stick. By Robert Preidt. medlineplus.gov. September 24, 2017. Dermatology expert offers advice on tick removal and avoiding them in the first place. As tick populations and the threats they pose increase across the United States, people need to know how to deal with them, a skin doctor suggests.Ticks can cause serious illnesses such as Lyme disease, Rocky Mountain spotted fever, Powassan virus and alpha-gal syndrome (a red meat allergy). "Although most ticks do not carry disease, it's important to be mindful of these risks and keep an eye out while you're outdoors," Dr. Lindsay Strowd said in an American Academy of Dermatology news release.

FULL ARTICLE...
Posted by jcp on Martes, septiembre 26 @ 00:00:00 ART (54 reads)

  Brain damage in fish induced by plastic nanoparticles delivered through the food chain

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Un pez muerto flotando (Photo: SerTox)

Brain damage in fish from plastic nanoparticles in water. sciencedaily.com. September 25, 2017. Summary: A new study shows that plastic particles in water may end up inside fish brains. The plastic can cause brain damage, which is the likely cause of behavioral disorders observed in the fish.
Calculations have shown that 10 per cent of all plastic produced around the world ultimately ends up in the oceans. As a result, a large majority of global marine debris is in fact plastic waste. Human production of plastics is a well-known environmental concern, but few studies have studied the effects of tiny plastic particles, known as nanoplastic particles.


FULL ARTICLE...
Posted by jcp on Martes, septiembre 26 @ 00:00:00 ART (91 reads)

  More about fipronil egg contamination II

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Fipronil (Photo: WP)

Update on Fipronil in Eggs. food.gov.uk. September 21, 2017. We continue to trace the distribution of eggs from farms in the Netherlands and Belgium affected by Fipronil. Since our previous update, one additional product has been withdrawn, as detailed in our updated withdrawal list. This is a waffles product, sold in smaller retail stores and catering outlets. Products must be removed from sale if the amount of implicated egg is more than 15% of the final product. Food businesses must comply with this or show that the egg ingredient used is compliant with the EU maximum residue level. The FSA continues to  work with the European Commission and we are being updated on investigations by other member states as further information comes to light.


FULL ARTICLE...
Posted by jcp on Viernes, septiembre 22 @ 00:00:00 ART (44 reads)

  CDC: death rate from drug overdoses more than doubled, and from opioids more than tripled

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Sobredosis de metadona y otros opioides (Photo: CDC)

Opioid ODs Have Cut Into U.S. Life Expectancy: CDC. medlineplus.gov. September 20, 2017. Doctors must start treating addiction, expert says.Rising death rates from opioid abuse are chipping away at Americans' life spans, a U.S. government study finds.Between 2000 and 2015, researchers found, U.S. life expectancy increased overall -- from nearly 77 years to 79 years.But buried within that broad pattern were some ominous trends. The death rate from drug overdoses more than doubled, while that from opioids, specifically, more than tripled, said lead researcher Dr. Deborah Dowell. She is with the U.S. Centers for Disease Control and Prevention's division of unintentional injury prevention.

FULL ARTICLE...
Posted by jcp on Jueves, septiembre 21 @ 00:00:00 ART (21 reads)

 Even after years of smoking, the body has a remarkable ability to repair itself

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Aquí han fumado... (Photo: Sertox )

Smokers who quit have metabolite levels that resemble those of nonsmokers. sciencedaily.com. September 20, 2017. Even after years of smoking, the body has a remarkable ability to repair itself. Now in a study shows that certain metabolic changes occur soon after quitting, and thesEven after years of smoking, the body has a remarkable ability to repair itself. Now in a study appearing in ACS' Journal of Proteome Research, scientists report that certain metabolic changes occur soon after quitting, and these changes could help explain how some ill-effects of smoking might be reversible.


FULL ARTICLE...
Posted by jcp on Miércoles, septiembre 20 @ 00:00:00 ART (33 reads)

 A growing number of children & teens are turning up in US emergency departments dependent on opioids

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Sobredosis de metadona y otros opioides (Photo: CDC)

More U.S. Kids Landing in ER With Opioid Addiction. medlineplus.gov. September 15, 2017. Researcher calls findings an emerging public health issue. A growing number of children and teens are turning up in U.S. emergency departments dependent on opioids -- including prescription painkillers and heroin, a new study finds.Researchers found that in 2013, nearly 50,000 ER patients aged 21 and younger were diagnosed with opioid dependence or addiction. That was up from just over 32,200 in 2008. By that final year, roughly 135 kids were testing positive for opioid dependence each day in the nation's emergency departments, the researchers said.

FULL ARTICLE...
Posted by jcp on Miércoles, septiembre 20 @ 00:00:00 ART (30 reads)

 EFSA report copied and pasted analyses from a Monsanto study

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Blanco o negro (Photo: Sertox )

EU report on weedkiller safety copied text from Monsanto study. By Arthur Neslen. theguardian.com.September 15, 2017. EU’s food safety watchdog recommended that glyphosate was safe but pages of report were identical to application from pesticide maker.The European food safety authority (Efsa) based a recommendation that a chemical linked to cancer was safe for public use on an EU report that copied and pasted analyses from a Monsanto study, the Guardian can reveal.Glyphosate is the core ingredient in Monsanto’s $4.75bn (£3.5bn) a year RoundUp weedkiller brand and a battle over its relicensing has split EU countries, with a final decision on its authorisation expected in early November.

FULL ARTICLE...
Posted by jcp on Sábado, septiembre 16 @ 00:00:00 ART (110 reads)

 Advice on pain management and proper disposal of unused opioid medications

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Sobredosis de metadona y otros opioides (Photo: CDC)

What You Can Do to Help Fight the Opioid Epidemic. By Robert Preidt. medlineplus.gov. September 13, 2017. A surgeon's group offers a blueprint for safer pain management. Proper disposal of prescription painkillers and use of safe alternatives to manage pain could help combat America's opioid abuse epidemic, doctors say. "Today, we are in the midst of an opioid crisis," said Dr. David Ring, chairman of the American Academy of Orthopaedic Surgeons' (AAOS) Committee on Patient Safety. In 2015, about 12.5 million Americans misused prescription opioids (such as OxyContin and Vicodin) and more than 15,000 overdose deaths were attributed to the drugs, according to the U.S. Department of Health and Human Services.

FULL ARTICLE...
Posted by jcp on Viernes, septiembre 15 @ 00:00:00 ART (28 reads)

 Prenatal supplements of Folic Acid may help reduce harms of pesticide exposure

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Ácido fólico (Photo: WP)

Could Folic Acid Fight a Cause of Autism? By Robert Preidt. medlineplus.gov. September 8, 2017. Prenatal supplements may help reduce harms of pesticide exposure, study suggests. By taking folic acid around the time of conception, mothers-to-be may reduce their child's risk of pesticide-related autism, a new study suggests. "We found that if the mom was taking folic acid during the window around conception, the risk associated with pesticides seemed to be attenuated," said study first author Rebecca Schmidt. "Mothers should try to avoid pesticides. But if they live near agriculture, where pesticides can blow in, this might be a way to counter those effects," said Schmidt. She is an assistant professor of public health sciences at the University of California, Davis.

FULL ARTICLE...
Posted by jcp on Martes, septiembre 12 @ 00:00:00 ART (30 reads)

 Link between antidepressant use in pregnancy and increased risk of psychiatric disorders

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Exposición prenatal a ... (Photo: SerTox)

Mom-to-Be's Antidepressants Tied to Kids' Psychiatric Woes. By Robert Preidt. medlineplus.gov.  September 07, 2017. But study authors say findings need to be interpreted with caution. Children whose mothers took antidepressants during pregnancy may be at increased risk for psychiatric disorders themselves, a new study suggests.Researchers reviewed data from more than 905,000 children born in Denmark between 1998 and 2012. The children's health was followed for up to 16.5 years. During the follow-up period, 32,400 of the children were diagnosed with a psychiatric disorder.


FULL ARTICLE...
Posted by jcp on Lunes, septiembre 11 @ 00:00:00 ART (35 reads)

 E-cigarettes can help smokers quit, but if they discard tobacco in favor of vaping nearly every day

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Cigarrillo electrónico en uso (Photo: elmundo.es)

E-Cigs May Help Smokers Quit, But … … Only if vaping is done 2 of every 3 days a month, study finds. medlineplus.gov. August 31, 2017. E-cigarettes can help smokers quit, but only if they discard tobacco in favor of vaping nearly every day, a new study suggests.Former smokers are nearly three times more likely to abstain from cigarette smoking if they puff on an e-cigarette two out of every three days a month, according to the analysis of a federal survey on smoking. "E-cigarettes are an effective way to get cigarette smokers to quit, but you really need to use those e-cigarettes," said lead researcher David Levy. "Using them a couple days a month isn't going to be anywhere near as effective as if you use them most, if not all, days in a month."

FULL ARTICLE...
Posted by jcp on Martes, septiembre 05 @ 00:00:00 ART (34 reads)

 Fentanyl is a key player in continuing epidemic of opioid-related overdose deaths in US

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Sobredosis de metadona y otros opioides (Photo: CDC)

Fentanyl Drives Rise in Opioid-Linked Deaths in US. medlineplus.gov. August 31, 2017. The synthetic drug is more powerful than heroin or morphine. Fentanyl, a synthetic narcotic, is a key player in America's continuing epidemic of opioid-related overdose deaths, two new studies report.Opioid OD deaths began increasing early this decade as people addicted to prescription painkillers started switching to heroin, which became cheaper and increased in supply, researchers from the U.S. Centers for Disease Control and Prevention said.But the emergence of fentanyl and its cousins drove an even greater increase in overdose deaths, exacerbating an already terrible situation, the researchers said. In 2015 alone, about 33,000 people died of an opioid overdose in the United States.

FULL ARTICLE...
Posted by jcp on Martes, septiembre 05 @ 00:00:00 ART (36 reads)

 The fipronil contaminated egg scandal is spreading to more and more countries

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Fipronil contaminated egg found in 45 countries. nltimes.nl. By Janene Pieters. September 5, 2017. The fipronil contaminated egg scandal is spreading to more and more countries. Since it was discovered that the toxic pesticide was used illegally in the Netherlands and Belgium a few months ago, 45 countries found fipronil in their eggs and egg products, the Telegraaf reports. Of the 28 EU member states, 26 reported finding fipronil in their eggs and egg products, European Commissioner Vytenis Andriukaitis of Health and Food Safety said on Tuesday. Only Lithuania and Croatia haven't reported finding the pesticide. The pesticide was also found in products in other countries like the United States, Russia, South Africa, the Dutch Antilles, Turkey, Iraq, Norway, Israel and Canada.

FULL ARTICLE...
Posted by jcp on Martes, septiembre 05 @ 00:00:00 ART (30 reads)

 More about fipronil egg contamination

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Fipronil (Photo: WP)

Fipronil egg contamination scandal and consequences for the food chain: update.europarl.europa.eu. September 01, 2017.
 Oeuf fipronil A representative from the Commission’s DG SANTE updated the AGRI Committee on Thursday morning on the state-of-play of the scandal related to the illegal use of the active substance Fipronil in laying hen farms in several Member States and its consequences in the whole EU food supply chain. Most Member States have been affected by the withdrawal of eggs or processed products containing eggs.  Committee Members were eager to obtain more information on the situation and expected implications for the farming sector.

permalink Posted by jcp on Lunes, septiembre 04 @ 00:00:00 ART (64 reads)

 Studies found a link between water turbidity and acute gastrointestinal illness incidence

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Una flor en un vaso de agua limpia (Photo: Sertox )

How Safe Is Your Drinking Water? Take a Look. By Randy Dotinga. medlineplus.gov. August 23, 2017. Even 'allowable' cloudiness could cause tummy troubles, study says. Even if local health officials say it's safe, cloudy drinking water may have the potential to cause vomiting and diarrhea, a new research review finds. Researchers looked at past North American and European studies exploring the link between water cloudiness, or turbidity, and tummy troubles. "More than 10 studies found a link between water turbidity and acute gastrointestinal illness incidence," said researcher Anneclaire De Roos.


FULL ARTICLE...
Posted by jcp on Lunes, agosto 28 @ 00:00:00 ART (37 reads)





     Trivia
 Trivia # 351: Bauhinia forficata

Toxicological trivia from September 02, 2016: Bauhinia forficata, commonly known as Brazilian orchid tree, Pata de Vaca,  is a species of flowering tree in the pea family, Fabaceae, that is native to Argentina, Brazil and Peru.Its flowers are white and pinkish, and is similar to an orchid. Deciduous leaves are lobed and the name "pata de vaca" resemble the imprint of a hoof there. It timber, known as false mahogany advantage, although its most widespread use is as a medicinal plant. In this sense, they have been well studied by their properties as:
a) Hypoglycemic and diuretic;
b) It is also used as an astringent, healing and antiseptic;
c) Both previous assertions are correct.




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