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PHONE OPEN: 00-54-341-4480202.Visit also our Spanish page. In SERTOX we don't use anymore the term ACCIDENT. [ See ]
 NEW! May - June 2010 Newsletter: See |
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 | WHO recommended classification of pesticides by hazard, 2009 |
The WHO recommended classification of pesticides by hazard And Guidelines to Classification 2009.July 15, 2010.This publication sets out a classification system to distinguish between the more and the less hazardous forms of selected pesticides based on acute risk to human health (that is the risk of single or multiple exposures over a relatively short period of time). It takes into consideration the toxicity of the technical compound and its common formulations. See PDF
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Posted by jcp on Miércoles, julio 28 @ 00:00:00 ART (2 reads)
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| China dairy products with melamine, again |
China dairy products found tainted with melamine. bbcnews. July 09, 2010. Chinese food safety officials have seized 64 tonnes of raw dairy materials contaminated with the toxic industrial chemical melamine. The Chinese state news agency, Xinhua, reported that the quality watchdog in Qinghai province took the material from a dairy plant there. Test samples showed the milk powder carried up to 500 times the maximum allowed level of the chemical. The use of melamine in milk in 2008 killed six babies and made 300,000 ill. The latest batch of contaminated powder was first found in Gansu province and traced back to the Dongyuan Dairy Factory in Minhe Country, in neighbouring Qinghai. Another 12 tonnes of finished milk powder products, also found to be tainted, were seized.[ See ]
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Posted by jcp on Miércoles, julio 14 @ 00:00:00 ART (28 reads)
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| Tackling injecting drug use in BMJ |
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Posted by jcp on Miércoles, julio 14 @ 00:00:00 ART (35 reads)
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| MERCOSUR health ministers' declaration, June 2010. |
"Attached, translated into English, is the wonderful Declation signed last month by the health ministers of nine South American countries, calling for a ban on all forms of asbestos and products containing asbestos. It would be wonderful if there is a way to to use this Declaration and make a public request to the health ministers of other countries, such as Mexico and Colombia, to support the leadership shown by these health ministers to stop the global South from being the dumping ground of deadly asbestos, with all the health and economic disaster it brings. It is to her enormous shame that Canada's Minister of Health, Leona Aglukkaq, continues to support asbestos use. It is an aberration that a Minister of Health would reject the position of the Canadian Medical Association, the Canadian Cancer Society, the Canadian Public Health Association and the 9,500 doctors in Quebec, who all have said that her position that chrysotile asbestos can be safely used is false and that Canada's mining and export of asbestos must end. It would be wonderful if people would send a short, sharp letter to Prime Minister Harper (Alukkaq has very little power) calling on him to support Canada's leading health authorities and put health ahead of politics. Ask him to let Canada's health authorities set his policy on asbestos, not the asbestos industry. Or whatever you wish to say. Harper is feeling the heat because of the demonstrations around the world and the letters they sent to him and all the media coverage at the moment. I am sure that his political advisers are chewing on this right now. So the more we do to let him know that we will not go away, he cannot bury the issue, we will expose, challenge and embarrass him, will help push them to decide the price for supporting asbestos is too high and too politically dangerous".Kathleen Ruff. Northwest Institute for Bioregional Research . Canada
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Posted by jcp on Sábado, julio 03 @ 00:00:00 ART (21 reads)
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| From DOAJ team to RETEL: Publishing practices in general |
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Your views on open access publishing are needed!. June 22, 2010. The SOAP Project (*) is currently conducting an online survey to assess researcher experiences with open access publishing. This survey aims to inform the most comprehensive analysis of attitudes to open access publishing to date and is seeking views from a wide a range of interested parties. It is primarily aimed at active researchers in public and private organizations, from all fields of the research in the sciences and humanities and focuses on publication of research articles in (open access) peer-reviewed journals. If you would like to contribute to shaping the public discourse on open access, please visit http://surveymonkey.com/soap_survey_g .It should take 10-15 minutes to complete. Please share this news with your research collaborators, so that the views from your community will be properly represented.The survey outcome will be made public and openly shared with the publishers, research funding agencies and European Commission, libraries and researchers. Thanks in advance, the SOAP Project Team
(*) The SOAP consortium is funded by the European Commission and coordinated by CERN, the European Organization for Nuclear Research. It represents key stakeholders in open access, such as publishers BioMed Central, SAGE and Springer; funding agencies (the UK Science and Technology Facilities Council) and libraries (the Max Planck Digital Library of the Max Planck Society). The project runs for two years, from March 2009 to February 2011.
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Posted by jcp on Miércoles, junio 23 @ 00:00:00 ART (44 reads)
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| ARBs links to increased risks for Cancer |
Research Links ARBs To Increased Risk Of Cancer. June 14, 2010.The AP (6/14,
Cheng) reports that, "in an analysis of
five previous studies following about 60,000 patients, experts found a link
between people taking medicines known as angiotensin-receptor blockers, or ARBs,
and cancer." Investigators "researchers found that people who took the drugs had
about a one percent higher risk of getting cancer than people who weren't on the
drugs. This included a whole range of cancers - prostate, breast and a
noticeable spike in lung cancer." The research is published online in the Lancet
Oncology.The Cleveland
Plain Dealer (6/14, Townsend) reports, however, that the researchers
said "We need more studies. We need more analysis to further clarify the
risk."The UK's Daily
Mail (6/14, Martin) reports, "The findings showed that 7.2 per cent of
patients taking ARBs were diagnosed with a new cancer over a period of four
years, compared with six per cent of patients not treated with the drugs." The UK's Press
Association (6/14) reports that "more than 85% of the patients were
taking one type of ARB, telmisartan." Bloomberg
News (6/14, Matsuyama) reports, however, that "Astellas Pharma Inc. and
Boehringer Ingelheim GmbH said" that "telmisartan...is safe based on patient
studies, refuting" the new "finding." MedPage
Today (6/13, Smith) reported that the researchers "said their analysis
was prompted by the result of a 2003 trial of one of the drugs, which showed an
unexpected increase in the proportion of fatal cancers among those getting the
medication." BBC
News (6/14, Wilkinson) reports that "it is not clear why ARBs may
increase cancer risk, but some animal studies suggest there may be a link with
blood vessel growth in tumours."The CNN (6/13,
Falco) "Paging Dr. Gupta" blog reported that "in an accompanying editorial,
Dr. Steven Nissen, chairman of the Department of Cardiovascular Medicine at the
Cleveland Clinic...suggests the results of this analysis require 'urgent
regulatory review.'" But, "Dr. Nicholas Vogelzang, an expert on several cancers
and spokesman for the American Society of Clinical Oncology disagrees. He says
he's fairly skeptical about the study conclusion, because the only statistically
significant rise was in lung cancer." The Wall
Street Journal (6/14, Loftus), Reuters (6/14,
Steenhuysen), HeartWire (6/13,
Nainggolan), and HealthDay (6/13,
Edelson) also covered the story. .
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Posted by jcp on Lunes, junio 14 @ 00:00:00 ART (45 reads)
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| EPA is taking action to end all uses of the insecticide endosulfan in the United States |
EPA Moves to Terminate All Uses of Insecticide Endosulfan to Protect Health of Farmworkers and Wildlife. yosemite.epa.gov.June 09, 2010. The U.S. Environmental Protection Agency (EPA) is taking action to end all uses of the insecticide endosulfan in the United States. Endosulfan, which is used on vegetables, fruits, and cotton, can pose unacceptable neurological and reproductive risks to farmworkers and wildlife and can persist in the environment. Read more....
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Posted by jcp on Lunes, junio 14 @ 00:00:00 ART (27 reads)
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| Trivia # 169: vodka drip therapy |
Toxicological trivia from June 10, 2010: Australian doctors in October 2007, have kept an Italian tourist alive by feeding him vodka through a drip for three days, medical staff in Queensland say. The 24-year-old man, who had swallowed a poison in an apparent suicide attempt, was treated while in a coma. Doctors set up the drip after running out of medicinal alcohol, used as an antidote to the poison. Medical staff said the patient had made a full recovery, and the hangover had worn off by the time he woke up. He had been taken to hospital in the northern Queensland town of Mackay after swallowing:
a) Ethylene glycol;
b) Methanol;
c) Propilenglycol.
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FULL ARTICLE...
Posted by jcp on Jueves, junio 10 @ 00:00:00 ART (51 reads)
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| European Survey of Enterprises on New and Emerging Risks (ESENER) |
The European Survey of Enterprises on New and Emerging Risks (ESENER, Publishing Date: 02/06/10 ) asks managers and workers' health and safety representatives about how health and safety risks are managed at their workplace, with a particular focus on the newer ‘psychosocial risks’, such as work-related stress, violence and harassment. This report presents an overview of the results from a first analysis of the data, which is drawn from 36,000 interviews carried out in 31 countries.Author:European Agency for Safety and Health at Work . See. PDF format.
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Posted by jcp on Miércoles, junio 09 @ 00:00:00 ART (47 reads)
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| BMJ, European group criticize WHO pandemic actions |
In CIDRAP News, by Robert Roos and Lisa Schnirring. Jun 4, 2010. An article published by the British Medical Journal says three scientists who helped frame World Health Organization (WHO) guidance on pandemic influenza preparedness had consulted for pharmaceutical companies that stood to profit from the WHO guidance and that the WHO did not disclose the scientists' industry ties. The lengthy report, published online yesterday, says the scientists had declared their industry connections in other publications, but the WHO did not reveal them in its guidance document, WHO Guidelines on the Use of Antivirals and Vaccines During an Influenza Pandemic, issued in 2004. The report also raises other questions about the WHO's transparency and its management of potential conflicts of interest. In particular, it is critical of the WHO's refusal to reveal the names of the members of its Emergency Committee, which was set up to help guide the WHO response to the H1N1 pandemic, including when to change pandemic alert phases. The secrecy fuels conspiracy theories about issues such as the triggering of vaccine contracts, the article says. Read more....
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FULL ARTICLE...
Posted by jcp on Sábado, junio 05 @ 00:00:00 ART (48 reads)
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| Trivia # 165: Nonselective Nonsteroidal Antiinflammatory Drugs and Cardiovascular Risk |
Toxicological trivia from June 03, 2010: Nonselective Nonsteroidal Antiinflammatory Drugs and Cardiovascular Risk: Are They Safe? Currently available data are insufficient for defining evidence-based clinical guidelines for the use of NSAIDs, and the need for additional research, specifically randomized controlled trials, is evident. Although the current clinical evidence may not warrant recommending:
a) Naproxen as the preferred NSAID treatment;
b) It may be prudent to avoid diclofenac for patients with cardiovascular risk factors requiring NSAID treatment:
c) Both previous assertions are correct.
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FULL ARTICLE...
Posted by jcp on Jueves, junio 03 @ 00:00:00 ART (31 reads)
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| New paper from Daniel Lerda |
Allium cepa as a biomonitor of ochratoxin A toxicity and genotoxicity. Lerda D, Biagi Bistoni M, Pelliccioni P & Litterio N.Plant Biology. Volume 9999 , Issue 9999 , Pages - Early View (Articles online in advance of print).Published Online: 29 Mar 2010.© 2010 German Botanical Society and Royal Botanical Society of the Netherlands
Abstract: Ochratoxin A (OTA) is a toxin produced by Aspergillus and Penicillum moulds.Since OTA has not yet been evaluated in plant systems, this paper focused on describing the controversial effect OTA in an Allium root test model, which has known sensitivity to genotoxins and could be useful in toxin screening. Analyses of root growth and the root meristematic zone in response to OTA treatment were undertaken. The results show OTA toxicity to root growth at a concentration of 10 ugÆml)1 associated with inhibition of proliferation activity. Cytological changes observed in the Allium chromosome aberrations assay, at a concentration of 5.0 ugÆml)1, showed that OTA was able to induce genotoxicity at the chromosome level. These results indicate that plants cells (Allium cepa) are very sensitive to the mycotoxin OTA, as observed at the highest concentration. Under these conditions, OTA produced toxicity and cytogenetic injury. Evidence in vitro and in vivo indicates that OTA can induce damage at the DNA level. Full PDF Text
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Posted by jcp on Miércoles, junio 02 @ 00:00:00 ART (66 reads)
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| About lead ingested in the meat of game animals |
Potential Hazard to Human Health from Exposure to Fragments of Lead Bullets and Shot in the Tissues of Game Animals. Pain DJ, Cromie RL, Newth J, Brown MJ, Crutcher E, et al. 2010. PLoS ONE 5(4): e10315. doi:10.1371/journal.pone.0010315. The potential health hazard from lead ingested in the meat of game animals may be larger than previous risk assessments indicated, especially for vulnerable groups, such as children, and those consuming large amounts of game. Full text
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Posted by jcp on Jueves, mayo 27 @ 00:00:00 ART (121 reads)
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| About metformin and vitamin B-12 deficiency |
Long term treatment with metformin in patients with type 2 diabetes and risk of vitamin B-12 deficiency: randomised placebo controlled trial. Jolien de Jager, Adriaan Kooy, Philippe Lehert, et al. BMJ 2010;340:c2181 . Published 20 May 2010, doi:10.1136/bmj.c2181. Full text. See abstact
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Posted by jcp on Miércoles, mayo 26 @ 00:00:00 ART (115 reads)
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| About phantasmal poison frogs at Blue Reef |
Success in breeding poison frogs at Portsmouth aquarium. portsmouth.co.uk. April 29, 2010.An aquarium has had success breeding dozens of deadly endangered frogs. Staff at the Blue Reef Aquarium in Southsea are celebrating after breeding phantasmal poison frogs - believed to be one of the most toxic amphibians on the planet. Measuring less than a centimetre in length, the tiny frogs' poison is believed to be 200 times more powerful than morphine. Usually bright red with three green fluorescent stripes, they are found only on the western slopes of the Andes in Ecuador. Blue Reef Aquarium's Jenna MacFarlane said: 'These beautiful frogs are under increasing threat in the wild due to loss of habitat and pollution and we are delighted to have been able to breed them successfully here in Portsmouth, 'It's important we are able to mimic exactly their wild environment in order for the species to thrive in captivity and it's a real achievement they are breeding so successfully. 'They've passed the critical stage of development from tadpoles into froglets and they now look like perfect miniature replicas of their parents.' The World Conservation Union considers the species to be under threat of extinction in the wild. And despite their deadly poison it is hoped that the phantasmal arrow frog could one day help save lives. Scientists discovered that an extract from the skin of a phantasmal poison frog can block pain 200 times more effectively than morphine.
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Posted by jcp on Lunes, mayo 24 @ 00:00:00 ART (78 reads)
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| Global strategy to combat alcohol abuse |
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| Bebidas alcoholicas (Photo: Sertox  ) |
WHO adopts global strategy to combat alcohol abuse. behavioralhealthcentral. May 20, 2010. Nations adopted a global strategy to reduce alcohol abuse on Thursday, breaking decades of silence on one of the leading causes of death and facing down an industry wary of new taxes and advertising controls in developing markets. In a consensus vote, the World Health Organization's 193 member states endorsed a series of optional measures to combat harmful drinking, from lowering blood alcohol limits for drivers to restricting opening hours of bars and liquor stores. The most contentious proposals affect brewers and liquor manufacturers, and deal with pricing and marketing. "Alcohol is the risk factor for many other things," said Dr. Shekhar Saxena, director of WHO's mental health and substance abuse department. "Usually it is not perceived as the killer, but it is." Read more,,,
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FULL ARTICLE...
Posted by jcp on Jueves, mayo 20 @ 00:00:00 ART (43 reads)
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| Trivia | |
| Trivia # 144: Mexican mushrooms |
Toxicological Trivia from March 23, 2010: Teófilo Herrera, emeritus researcher at UNAM, in Mexico, said in an interview that, according to estimation in the world has a million and a half varieties of mushrooms, while in Mexico there is 60 thousand, which are known only on:
a) 4.5%;
b) 17%;
c) 34%.
READ ANSWER...
See all: Toxicological trivia |
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